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Combined mechanical and pharmacological approach to a thrombus‐containing lesion
Author(s) -
BenDor Itsik,
Pichard Augusto D.,
Waksman Ron
Publication year - 2010
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.22387
Subject(s) - medicine , thrombus , myocardial infarction , percutaneous coronary intervention , lesion , embolization , percutaneous , cardiology , radiology , acute coronary syndrome , perfusion , thrombolysis , surgery
Abstract Distal embolization during primary percutaneous coronary intervention for acute myocardial infarction is associated with impaired myocardial perfusion and poor outcome. Numerous pharmacological and mechanical strategies have been proposed to prevent and treat distal embolization. A successful combined mechanical and pharmacological approach to a large thrombus‐containing lesion in patients with acute coronary syndrome is described. A review of the current literature regarding the drugs and devices available for the prevention and treatment of large thrombus burden has also been performed. © 2010 Wiley‐Liss, Inc.