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Determination of adequate coronary stent expansion using StentBoost, a novel fluoroscopic image processing technique
Author(s) -
Mishell Jacob M.,
Vakharia Kalpesh T.,
Ports Thomas A.,
Yeghiazarians Yerem,
Michaels Andrew D.
Publication year - 2007
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.20901
Subject(s) - medicine , stent , intravascular ultrasound , restenosis , coronary angiography , radiology , fluoroscopy , coronary stent , calcification , angiography , nuclear medicine , cardiology , myocardial infarction
Objective: We tested the hypothesis that the use of motion‐corrected fluoroscopic images results in enhanced coronary stent visualization and improved detection of inadequate stent expansion.Background: Intravascular ultrasound (IVUS) more accurately detects inadequate stent expansion when compared with coronary angiography. Stent under‐expansion is associated with stent restenosis and thrombosis. Developing a technique to improve fluoroscopic‐based assessment of stent expansion is desirable.Methods: We analyzed measurements of 48 coronary stents implanted in 30 patients using quantitative coronary angiography (QCA), IVUS, and StentBoost (SB), a novel fluoroscopic image processing technique. Correlations of stent diameter between the modalities were determined. Using established IVUS criteria for adequate stent deployment, we assessed the diagnostic test characteristics of SB to detect inadequate stent expansion.Results: Correlations of minimum stent diameter were highest between IVUS and SB ( r = 0.75; P < 0.0001) when compared with QCA and IVUS ( r = 0.65; P < 0.0001), and QCA and SB ( r = 0.49; P = 0.0004). IVUS and SB demonstrated a small difference in minimum stent diameter, 0.043 mm (95% CI: 0.146–0.061 mm). The correlation between IVUS and SB was lower for vessels with intimal calcification ( r = 0.57; P = 0.002) when compared with vessels with deeper calcification ( r = 0.84; P < 0.0001). A SB minimum diameter of <2.5 mm predicted inadequate stent expansion by IVUS with 88% sensitivity, 70% specificity, and a positive likelihood ratio of 2.9.Conclusions: SB had superior correlations for stent expansion measured by IVUS when compared with QCA. A minimum stent diameter by SB measurement <2.5 mm is associated with inadequate stent expansion using IVUS criteria. © 2006 Wiley‐Liss, Inc.