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Renal frame count: A quantitative angiographic assessment of renal perfusion
Author(s) -
Mulumudi Mahesh S.,
White Christopher J.
Publication year - 2005
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.20383
Subject(s) - medicine , fibromuscular dysplasia , perfusion , renal artery , kidney , renal function , cardiology , angiography , radiology , urology
Renal perfusion may be measured by a variety of noninvasive methods; however, there is no objective angiographic method to assess renal perfusion. We measured the renal frame count (RFC) in 26 patients (50 kidneys) with normal renal function and normal renal angiograms and 9 patients (15 kidneys) with renal artery fibromuscular dysplasia (FMD) and normal renal function. The mean age of the patients with normal renal arteries was 61.5 ± 9.5 (range, 47–82 years) and the mean age of patients with FMD was 72.5 ± 9.2 (range, 54–86 years; P = 0.005). There was no correlation between the age and RFC in both the normal renal artery group and the FMD group. The mean RFC for the normal renal arteries was 20.4 ± 3 (95% CI = 19.5–21.2), which was significantly lower than the FMD group's mean RFC of 26.9 ± 9.9 (95% CI = 21.4–32.4; P = 0.0001). RFC is an objective angiographic measure to quantify renal perfusion. Compared to normal renal arteries, those with FMD had significantly increased RFC consistent with decreased perfusion. © 2005 Wiley‐Liss, Inc.