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Percutaneous patent foramen ovale and atrial septal defect closure in adults: Results and device comparison in 100 consecutive implants at a single center
Author(s) -
Herrmann Howard C.,
Silvestry Frank E.,
Glaser Ruchira,
See Vincent,
Kasner Scott,
Bradbury Danielle,
Chang Gene,
Hirshfeld John W.,
Horwitz Phillip A.,
Kelly Michael
Publication year - 2005
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.20260
Subject(s) - medicine , patent foramen ovale , percutaneous , paradoxical embolism , foramen secundum , shunting , intracardiac injection , shunt (medical) , cardiology , cardiac catheterization , surgery , heart septal defect , single center
Abstract Closure of interatrial septal defects with percutaneous devices is increasingly common. However, the indications for closure and techniques for device implantation are diverse. We reviewed our first 100 consecutive implants to assess and compare the indications, results, complications, and evolution of techniques for percutaneous patent foramen ovale (PFO) and atrial septal defect (ASD) closure. The mean age of patients was 52 years and 70% were female. Paradoxical embolism was the predominant indication (94%) for PFO closure and significant left‐to‐right shunt was the most frequent indication (89%) for ASD closure. Implantation success was 94% with major complications in 3 patients (2.8%). Transesophageal echocardiography was utilized in the initial 27 procedures and then replaced by intracardiac echocardiography in subsequent ones, with an associated reduction in procedure and physician time. During 6 months of follow‐up, 3 patients were readmitted for atrial arrhythmias (2 patients) and an MRI‐negative neurologic event (1 patient). Echocardiography at 6 months in 83% of the PFO patients revealed moderate and severe positive contrast studies for right‐to‐left shunting in one third of patients, with differences between devices and insertion techniques. This single‐center experience with percutaneous device closure of PFO and ASD in adults demonstrates excellent results with few complications. Catheter Cardiovasc Interv 2005;64:197–203. © 2005 Wiley‐Liss, Inc.