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Angiographic adverse events during percutaneous coronary intervention fail to predict creatine kinase‐MB elevation
Author(s) -
Blankenship James C.,
Islam M. Ashequl,
Wood G. Craig,
Iliadis Elias A.
Publication year - 2004
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.20065
Subject(s) - medicine , percutaneous coronary intervention , adverse effect , cardiology , creatine kinase , coronary angiography , catheter , radiology , myocardial infarction
Abstract We attempted to determine if aggressive detection of angiographic adverse events during coronary intervention could predict subsequent creatine kinase (CK)‐MB elevations. During coronary intervention, both fluoroscopy and cine angiography were used to detect angiographic adverse events. At least one angiographic adverse event occurred in 133/251 (53%) of procedures. CK‐MB elevation occurred in 24% of procedures. Slow flow during the procedure ( P = 0.002) and chest discomfort at the end of the procedure ( P = 0.007) were the strongest predictors of CK‐MB elevation. Among procedures with no angiographic adverse events, CK‐MB elevation occurred in 15/121 (12%), accounting for 25% of CK‐MB elevations. We conclude that CK‐MB elevation occurs after angiographically uncomplicated coronary interventions even when angiographic adverse events are aggressively detected. Routine monitoring of cardiac enzymes is necessary to detect all patients who will experience myocardial injury after coronary intervention. Catheter Cardiovasc Interv 2004;63:31–41. © 2004 Wiley‐Liss, Inc.