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Randomized study of the safety and clinical utility of rotational angiography versus standard angiography in the diagnosis of coronary artery disease
Author(s) -
Maddux James T.,
Wink Onno,
Messenger John C.,
Groves Bertron M.,
Liao Robert,
Strzelczyk Jodi,
Chen ShiuhYung,
Carroll John D.
Publication year - 2004
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.20036
Subject(s) - medicine , rotational angiography , angiography , coronary artery disease , radiology , coronary angiography , artery , nuclear medicine , cardiology , myocardial infarction
This study evaluates the safety and clinical utility of rotational angiography in the diagnosis of coronary artery disease. High‐speed rotational angiography is a newly available angiographic modality that gives a dynamic multiple‐angle perspective of the coronary tree during a single contrast injection. We prospectively randomized 56 patients referred for diagnostic coronary angiography to either standard or rotational angiography. Contrast and radiation utilization were compared between the two groups. The number of additional cine acquisitions needed was used to determine adequacy of the diagnostic study protocol. Rotational angiography was successfully completed in all subjects. There was a 33% reduction in contrast utilization in the rotational group as compared to the standard group (35.6 ± 12.6 vs. 52.8 ± 10.7 ml, respectively; P < 0.0001). Additionally, there was a 28% reduction in total radiation exposure in the rotational group as compared to the standard group (39.0 ± 18.5 vs. 53.9 ± 23.4 Gycm 2 , respectively; P = 0.01). Total whole‐body radiation exposure to the primary operator was 144 mrem with rotational angiography and 170 mrem with standard angiography. Procedure time tended to be shorter for rotational angiography (353.9 ± 146.7 vs. 396.8 ± 165.8 s; P = 0.3). Rotational coronary angiography can be rapidly performed in any patient and provides a significant reduction in contrast and radiation utilization while at the same time providing adequate angiographic data to complement or replace standard coronary angiography in the evaluation of coronary artery disease. Catheter Cardiovasc Interv 2004;62:167–174. © 2004 Wiley‐Liss, Inc.