Abciximab for the treatment of acute distal embolization associated with internal carotid artery angioplasty

Carotid artery angioplasty and stent placement (CAS) can be complicated by procedure‐related distal embolization and thrombus formation, potentially resulting in neurological sequelae. Patient A had CAS of left internal carotid artery and had loss of vision in the left eye with no flow in the left ophthalmic artery. Patient B had CAS of right internal carotid artery and developed left sided hemiparesis with total occlusion of the right middle cerebral artery. A selective intra‐arterial injection of 5 mg of abciximab locally followed by a bolus of 5 mg of abciximab intravenously resulted in complete resolution of the filling defect on repeat angiography after 10 min in both patients. Cathet Cardiovasc Intervent 2001;54:221–233. © 2001 Wiley‐Liss, Inc.