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Abciximab for the treatment of acute distal embolization associated with internal carotid artery angioplasty
Author(s) -
Kittusamy Prem K.,
Koenigsberg Robert A.,
McCormick Daniel J.
Publication year - 2001
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.1273
Subject(s) - medicine , abciximab , angioplasty , embolization , internal carotid artery , thrombus , angiography , cardiology , occlusion , radiology , surgery , myocardial infarction , percutaneous coronary intervention
Abstract Carotid artery angioplasty and stent placement (CAS) can be complicated by procedure‐related distal embolization and thrombus formation, potentially resulting in neurological sequelae. Patient A had CAS of left internal carotid artery and had loss of vision in the left eye with no flow in the left ophthalmic artery. Patient B had CAS of right internal carotid artery and developed left sided hemiparesis with total occlusion of the right middle cerebral artery. A selective intra‐arterial injection of 5 mg of abciximab locally followed by a bolus of 5 mg of abciximab intravenously resulted in complete resolution of the filling defect on repeat angiography after 10 min in both patients. Cathet Cardiovasc Intervent 2001;54:221–233. © 2001 Wiley‐Liss, Inc.