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Intravascular ultrasound analysis of nonstented adjacent segments in diffuse in‐stent restenosis treated with radiation therapy with a rhenium‐188–filled balloon
Author(s) -
Hong MyeongKi,
Park SeongWook,
Moon DaeHyuk,
Oh SeungJun,
Lee Cheol Whan,
Kim YoungHak,
Lee JaeWhan,
Song JongMin,
Kang DukHyun,
Song JaeKwan,
Kim JaeJoong,
Park SeungJung
Publication year - 2003
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.10498
Subject(s) - medicine , restenosis , intravascular ultrasound , balloon , lumen (anatomy) , radiation therapy , stent , nuclear medicine , radiology , surgery
The effects of β‐radiation therapy on nonstented adjacent segments in in‐stent restenosis have not been sufficiently evaluated. β‐radiation therapy for in‐stent restenosis was performed with a 188 Re‐MAG 3 –filled balloon. We evaluated the effects of β‐radiation therapy on nonstented adjacent segments in in‐stent restenosis by intravascular ultrasound (IVUS) analysis in 50 patients who received radiation therapy vs. 9 control patients. The changes (Δ = follow‐up − postintervention) of the external elastic membrane (EEM), the lumen, and other IVUS variables were compared between the segments that received radiation therapy and the control segments. The significant differences between the two groups were as follows: Δ EEM area was 0.3 mm 2 in the radiation vs. −1.0 mm 2 in the control ( P = 0.005) and Δ lumen area was 0.2 mm 2 vs. −1.3 mm 2 , respectively ( P < 0.001). In conclusion, compared with the changes of vessel shrinkage in the control group, significant vessel enlargement occurred in the nonstented adjacent segments that received radiation therapy. Cathet Cardiovasc Intervent 2003;58:428–433. © 2003 Wiley‐Liss, Inc.