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Transcatheter patch occlusion of experimental atrial septal defects
Author(s) -
Sideris Eleftherios B.,
Sideris Chrysoula E.,
Stamatelopoulos Stamatis F.,
Moulopoulos Spyridon D.
Publication year - 2002
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.10333
Subject(s) - medicine , occlusion , atrial septum , patent foramen ovale , cardiology , balloon dilation , heart septal defect , foramen ovale (heart) , balloon , catheter , surgery , percutaneous
The effectiveness and safety of transcatheter patch atrial septal defect (ASD) occlusion were studied in 20 piglets. Experimental atrial septal defects were created by foramen ovale dilation. ASDs were corrected by polyurethane patches of two types (flat and sleeve). Specially made balloon catheters supported the patches for periods varying from 1 to 6 days; after this period, the supporting catheters were withdrawn and the patches were released. All transcatheter patches were safely embedded in the atrial septum 48 hr or more after implantation. All defects were fully occluded. One patch became infected. The transcatheter patch experimental ASD occlusion method was found effective and safe, potentially applicable in the occlusion of human ASDs. Cathet Cardiovasc Intervent 2002;57:404–407. © 2002 Wiley‐Liss, Inc.