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Does stent design affect the long‐term outcome after coronary stenting?
Author(s) -
Elbaz Meyer,
El Mokhtar Elyes,
Fourcade Joelle,
Mourali Sami,
Hobeika Robert,
Carrié Didier,
Puel Jacques
Publication year - 2002
Publication title -
catheterization and cardiovascular interventions
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.988
H-Index - 116
eISSN - 1522-726X
pISSN - 1522-1946
DOI - 10.1002/ccd.10240
Subject(s) - medicine , stent , cardiology , coronary artery disease , coronary stent , surgery , restenosis
The purpose of our study was to determine the clinical, angiographic, and procedural variables that predict the risk for 2‐year target lesion revascularization (TLR) and other clinical events in a large cohort of patients treated with coronary stenting. Between March 1996 and March 1999, 1,340 patients were prospectively enrolled. They underwent at least one stenting procedure with one of the four coronary stent types used during this time period in our institution: Wiktor‐I, Nir, Bard XT, or Tenax. Clinical follow‐up was obtained for 99.1% of eligible patients (mean, 19.38 ± 4.97 months). The overall TLR rate was 10.7% at 24 months. Two variables were independently associated with the long‐term outcome: MLD post stenting and stent type. Implantation of silicon carbide–coated stents was associated with a twofold decrease in 24‐month TLR ( P < 0.01). The major adverse cardiac event rate at 2 years was 20.8%. Multivariate analysis showed that three parameters were predictive: diabetes ( P < 0.002), recent onset of symptoms ( P < 0.03), and high diffusion of coronary atherosclerosis as assessed by Gensini score ( P < 0.0069). In conclusion, stent type, and particularly passive silicon carbide coating, appears to affect the 24‐month TLR rate but not other major cardiac events. Cathet Cardiovasc Intervent 2002;56:305–311. © 2002 Wiley‐Liss, Inc.