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Front Cover: Synthetic Phosphoethanolamine Cellobiose Promotes Escherichia coli Biofilm Formation and Congo Red Binding (ChemBioChem 15/2021)
Author(s) -
Nguyen Johny M.,
Moore Rebecca E.,
Spicer Sabrina K.,
Gaddy Jennifer A.,
Townsend Steven D.
Publication year - 2021
Publication title -
chembiochem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.202100244
Subject(s) - biofilm , escherichia coli , cellobiose , chemistry , cellulose , cellulosic ethanol , microbiology and biotechnology , congo red , biochemistry , biophysics , bacteria , biology , organic chemistry , gene , genetics , adsorption , cellulase
Escherichia coli produces a phosphoethanolamine modified cellulose that is required for extracellular matrix assembly and biofilm scaffolds. A synthetic phosphoethanolamine cellobiose mimics the behavior of the naturally occurring polymer, inducing curli production and increasing biofilm formation. The discovery has implications for understanding microbial biofilms and the generation of new cellulosic probes. More information can be found in the Full Paper by J. A. Gaddy, S. D. Townsend et al.