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Cover Feature: Synergistic Interactions Are Prevalent in Catalytic Amyloids (ChemBioChem 18/2020)
Author(s) -
Marshall Liam R.,
Jayachandran Megha,
LengyelZhand Zsofia,
Rufo Caroline M.,
Kriews Austin,
Kim MinChul,
Korendovych Ivan V.
Publication year - 2020
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.202000570
Subject(s) - histidine , chemistry , lysine , amino acid , glutamine , combinatorial chemistry , catalysis , tyrosine , hydrolysis , biochemistry , cover (algebra) , arginine , computational biology , biology , mechanical engineering , engineering
Just like a limited set of playing cards can provide many combinations, mixtures of peptides with different amino acids can form various functional materials. Even simple binary mixtures of heptapeptides can synergistically form catalytic amyloids with high (using arginine and glutamine), moderate (using lysine and glutamate), or low (using histidine and tyrosine) hydrolytic activities. More information can be found in the communication by I. V. Korendovych et al.