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Bridging “Big Data” and Mechanistic Insight To Enable Precision Medicine
Author(s) -
Douglass Eugene F.
Publication year - 2020
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.202000494
Subject(s) - bridging (networking) , precision medicine , data science , bridge (graph theory) , big data , computer science , mechanism (biology) , data mining , medicine , epistemology , computer security , philosophy , pathology
Realizing the promise of precision medicine will require breaking down communication barriers between genomic, screening and literature “big data.” We discuss the opportunities and challenges of reconciling data science approaches with the scientific method and the critical role of chemical biologists as a bridge between data and mechanism. Finally we propose next steps on the road to precision medicine and give examples of new tools designed to catalyze these steps.