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Nanofactories for Controlled Synthesis and Delivery of Nucleoside Analogue Therapeutics
Author(s) -
Ebrahimi Kourosh H.
Publication year - 2020
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.202000382
Subject(s) - nanomedicine , nanotechnology , action (physics) , nucleoside analogue , computer science , nucleoside , biochemical engineering , chemistry , engineering , materials science , physics , biochemistry , nanoparticle , quantum mechanics
The ultimate nanomedicine will be a cell‐like machinery capable of reaching a specific target in the body and performing a desired therapeutic action in a controlled fashion. To make such machinery a reality, we need to combine fundamental knowledge and technological developments in different areas including polymer chemistry, biology, enzymology, and biochemical engineering. In this viewpoint, I put forward my vision of creating a nanofactory as a step towards developing cell‐like nanomedicines. To make the proposed nanofactory a reality there are many challenges ahead. I propose plausible solutions to address some of the main challenges.