Cover Feature: Coculturing of Mosquito‐Microbiome Bacteria Promotes Heme Degradation in  Elizabethkingia anophelis  (ChemBioChem 9/2020) | Zendy

Ganley Jack G. | Zendy; D'Ambrosio Hannah K. | Zendy; Shieh Meg | Zendy; Derbyshire Emily R. | Zendy

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Cover Feature: Coculturing of Mosquito‐Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis (ChemBioChem 9/2020)

Author(s) -

Ganley Jack G.,

D'Ambrosio Hannah K.,

Shieh Meg,

Derbyshire Emily R.

Publication year - 2020

Publication title -

chembiochem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.202000216

Subject(s) - heme , biliverdin , microbiome , biology , pathogen , microbiology and biotechnology , bacteria , computational biology , chemistry , biochemistry , heme oxygenase , genetics , enzyme

Bacterial communities that reside in mosquitoes can influence host biology and pathogen transmission. Through coculturing of mosquito‐microbiome members, Elizabethkingia anophelis was identified as a dominant species. When grown with another microbiome member Pseudomonas sp., E. anophelis upregulates the heme‐binding protein HemS. We show that HemS degrades heme to biliverdin IX β and biliverdin IX δ . More information can be found in the communication by E. R. Derbyshire et al. on page 1279 in Issue 9, 2020 (DOI: 10.1002/cbic.201900675).

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