Premium
Cover Feature: Ascorbate Oxidase Mimetic Activity of Copper(II) Oxide Nanoparticles (ChemBioChem 7/2020)
Author(s) -
He ShaoBin,
Hu AiLing,
Zhuang QuanQuan,
Peng HuaPing,
Deng HaoHua,
Chen Wei,
Hong GuoLin
Publication year - 2020
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.202000169
Subject(s) - ascorbic acid , chemistry , dehydroascorbic acid , oxidase test , nanoparticle , copper , catalysis , combinatorial chemistry , nuclear chemistry , enzyme , biochemistry , organic chemistry , nanotechnology , materials science , food science
Cupric oxide nanoparticles (CuO NPs) are a new ascorbate oxidase mimetic nanozyme. In their full paper, H.‐H. Deng, W. Chen, G.‐L. Hong, et al. report how CuO NPs can catalyze the oxidation of ascorbic acid (AA) by dissolved O 2 as a green oxidant to form dehydroascorbic acid (DHAA). The apparent steady‐state kinetic parameters indicated that this new type of ascorbate oxidase mimic and natural ascorbate oxidase (AAO) have similar affinities for AA, whereas the robustness of CuO NPs is greater than that of AAO. Moreover, by coupling the CuO NP‐catalyzed oxidation of AA to the reaction between o ‐phenylenediamine and DHAA, a fluorescence sensor for AA detection was established. More details can be found in the full paper by H.‐H. Deng, W. Chen, G.‐L. Hong, et al. on page 978 in Issue 7, 2020 (DOI: 10.1002/cbic.201900595).