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Iron‐Based Nanozymes in Disease Diagnosis and Treatment
Author(s) -
Shi Chu,
Li Yan,
Gu Ning
Publication year - 2020
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.202000094
Subject(s) - biomedicine , nanotechnology , biochemical engineering , disease treatment , rational design , computer science , intensive care medicine , medicine , materials science , bioinformatics , biology , engineering
Iron‐based nanozymes are currently one of the few clinical inorganic nanoparticles for disease diagnosis and treatment. Overcoming the shortcomings of natural enzymes, such as easy inactivation and low yield, combined with their special nanometer properties and magnetic functions, iron‐based nanozymes have broad prospects in biomedicine. This minireview summarizes their preparation, biological activity, catalytic mechanism, and applications in diagnosis and treatment of diseases. Finally, challenges to their future development and the trends of iron‐based nanozymes are discussed. The purpose of this minireview is to better understand and reasonably speculate on the rational design of iron‐based nanozymes as an increasingly important new paradigm for diagnostics.