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Cover Feature: Analysis of Metal Effects on C‐Peptide Structure and Internalization (ChemBioChem 19/2019)
Author(s) -
Stevenson Michael J.,
Farran Ian C.,
Uyeda Kylie S.,
San Juan Jessica A.,
Heffern Marie C.
Publication year - 2019
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201900579
Subject(s) - peptide , internalization , chemistry , cover (algebra) , metal ions in aqueous solution , function (biology) , proinsulin , metal , biochemistry , combinatorial chemistry , biology , microbiology and biotechnology , receptor , insulin , organic chemistry , endocrinology , mechanical engineering , engineering
The proinsulin connecting peptide , C‐peptide, is released in equimolar amounts and might be an active hormone. The exact function of C‐peptide remains unclear, but its activity might depend on metal ions. As depicted in this cover art, bioavailable metals could be the missing piece to elucidate C‐peptide′s activity. More information can be found in the communication by M. C. Heffern et al. on page 2447 in Issue 19, 2019 (DOI: 10.1002/cbic.201900172).