Premium
Cover Feature: Automatic Full Glycan Structural Determination through Logically Derived Sequence Tandem Mass Spectrometry (ChemBioChem 18/2019)
Author(s) -
Tsai ShangTing,
Liew Chia Yen,
Hsu Chen,
Huang ShihPei,
Weng WeiChien,
Kuo YuHsiang,
Ni ChiKung
Publication year - 2019
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201900532
Subject(s) - chemistry , glycosidic bond , glycan , tandem mass spectrometry , mass spectrometry , monosaccharide , chromatography , fast atom bombardment , glycopeptide , sequence (biology) , diastereomer , tandem , stereochemistry , biochemistry , glycoprotein , enzyme , materials science , composite material , antibiotics
The structures of oligosaccharides , including the differentiation of the diastereomer and anomer of each monosaccharide and the identification of linkage positions of each glycosidic bond, can be determined by a new method: tandem mass spectrometry guided by a logically derived sequence (LODES). The entire procedure of mass spectrum measurement guided by LODES can be programmed in a computer for automatic structural identification of the oligosaccharides eluted from high‐performance liquid chromatography. More information can be found in the full paper by C.‐K. Ni et al. on page 2351 in Issue 18, 2019 (DOI: 10.1002/cbic.201900228).