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Cover Feature: Bimodal Detection of Proteins by 129 Xe NMR and Fluorescence Spectroscopy (ChemBioChem 11/2019)
Author(s) -
Mari Emilie,
Bousmah Yasmina,
Boutin Céline,
Léonce Estelle,
Milanole Gaelle,
Brotin Thierry,
Berthault Patrick,
Erard Marie
Publication year - 2019
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201900306
Subject(s) - nuclear magnetic resonance spectroscopy , chemistry , fluorescence spectroscopy , spectroscopy , fluorescence , fluorescence correlation spectroscopy , xenon , analytical chemistry (journal) , stereochemistry , physics , molecule , organic chemistry , quantum mechanics
A bimodal probe for protein detection that combines hyperpolarized 129 Xe NMR and fluorescence spectroscopy has been optimized. Fluorescence detection is performed by a ligand, CrAsH, that recognizes a target peptide fused to the specific protein. Detection through 129 Xe NMR spectroscopy is based on a cryptophane cage hosting xenon. More information can be found in the full paper by P. Berthault, M. Erard et al. on page 1450 in Issue 11, 2019 (DOI: 10.1002/cbic.201800802).