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Cover Feature: Involvement of β‐Alkylation Machinery and Two Sets of Ketosynthase‐Chain‐Length Factors in the Biosynthesis of Fogacin Polyketides in Actinoplanes missouriensis (ChemBioChem 8/2019)
Author(s) -
Sato Kei,
Katsuyama Yohei,
Yokota Kousuke,
Awakawa Takayoshi,
Tezuka Takeaki,
Ohnishi Yasuo
Publication year - 2019
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201900175
Subject(s) - polyketide , cover (algebra) , biosynthesis , substrate (aquarium) , feature (linguistics) , mycelium , stereochemistry , chemistry , biology , biochemistry , botany , enzyme , engineering , philosophy , mechanical engineering , ecology , linguistics
The cover feature picture shows a unique polyketide biosynthesis pathway in Actinoplanes missouriensis . β‐Alkylation machinery encoded by an HCS cassette and two sets of KS‐CLF with different starter substrate specificities enhances the structural diversity of its final products. The background shows A. missouriensis sporangia formed on substrate mycelium. More information can be found in the full paper by Y. Katsuyama, Y. Ohnishi, et al. on page 1039 in Issue 8, 2019 (DOI: 10.1002/cbic.201800640).