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Organic Semiconductors for Photothermal Therapy and Photoacoustic Imaging
Author(s) -
Wang Xuemei,
Geng Zhongmin,
Cong Hailin,
Shen Youqing,
Yu Bing
Publication year - 2019
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201800818
Subject(s) - photothermal therapy , photoacoustic imaging in biomedicine , materials science , nanoparticle , polymer , nanotechnology , conjugated system , photodynamic therapy , absorbance , chemistry , optics , organic chemistry , physics , chromatography , composite material
In recent years, semiconducting polymer nanoparticles (SPNs) have been attracting considerable attention because of their outstanding characteristics such as higher light and thermal stability. They are widely used in fields of biomedicine such as photoacoustic (PA) imaging (PAI), photodynamic therapy (PDT), and photothermal therapy (PTT). PAI, a new imaging modality based on PA effects, shows great promise in biomedical applications. SPNs that display strong optical absorbance in the visible and near‐infrared (NIR) regions can be promising candidates for in vivo PTT and PAI. Here we introduce the preparation of organic conjugated polymer fluorescent nanoparticles in the aqueous phase. We then discuss the application of water‐dispersible conjugated polymer nanoparticles in PA and PTT. Finally, we discuss the opportunities and challenges for the development of organic conjugated polymer nanoparticles.