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Biomedical Applications of Fluorescent and Magnetic Resonance Imaging Dual‐Modality Probes
Author(s) -
Deng Yun,
Xu Aifei,
Yu Yanhua,
Fu Cheng,
Liang Gaolin
Publication year - 2019
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201800450
Subject(s) - magnetic resonance imaging , modality (human–computer interaction) , molecular imaging , fluorescence , fluorescence lifetime imaging microscopy , nuclear magnetic resonance , molecular probe , biomedical engineering , materials science , computer science , radiology , chemistry , medicine , artificial intelligence , in vivo , biology , physics , biochemistry , optics , dna , microbiology and biotechnology
Molecular imaging plays a critical role in biomedical research. The combination of different modalities can generate complementary information and provide synergistic advantages over single modality alone. Noninvasive and nonradioactive fluorescent imaging (FI)/magnetic resonance imaging (MRI) dualmodality probes fuse the high sensitivity of FI and the high temporal and spatial resolution and deep‐tissue penetration of MRI, and their increasing applications have been reported in biomedical research and clinical practices, including cell labeling, enzyme activity measurement, tumor diagnosis and therapy, and anatomical localization and real‐time assessment during surgery.