Analysis of Interactions between Telomeric i‐Motif DNA and a Cyclic Tetraoxazole Compound | Zendy

Sedghi Masoud Shadi | Zendy; Yamaoki Yudai | Zendy; Ma Yue | Zendy; Marchand Adrien | Zendy; Winnerdy Fernaldo Richtia | Zendy; Gabelica Valérie | Zendy; Phan Anh Tuân | Zendy; Katahira Masato | Zendy; Nagasawa Kazuo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Analysis of Interactions between Telomeric i‐Motif DNA and a Cyclic Tetraoxazole Compound

Author(s) -

Sedghi Masoud Shadi,

Yamaoki Yudai,

Ma Yue,

Marchand Adrien,

Winnerdy Fernaldo Richtia,

Gabelica Valérie,

Phan Anh Tuân,

Katahira Masato,

Nagasawa Kazuo

Publication year - 2018

Publication title -

chembiochem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.201800425

Subject(s) - motif (music) , dna , stereochemistry , computational biology , chemistry , genetics , biology , combinatorial chemistry , nanotechnology , materials science , physics , acoustics

The interaction of a macrocyclic tetraoxazole compound, L2H2‐4OTD ( 1 ), with two aminoalkyl side chains and telomeric i‐motif, was investigated by means of electrophoretic mobility shift assay, circular dichroism spectroscopy, mass spectrometry and NMR spectroscopy analyses. The results indicate that 1 interacts with the i‐motif structure at two preferred binding sites.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research