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Cover Feature: Mannose‐Decorated Multicomponent Supramolecular Polymers Trigger Effective Uptake into Antigen‐Presenting Cells (ChemBioChem 9/2018)
Author(s) -
Straßburger David,
Stergiou Natascha,
Urschbach Moritz,
Yurugi Hajime,
Spitzer Daniel,
Schollmeyer Dieter,
Schmitt Edgar,
Besenius Pol
Publication year - 2018
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201800191
Subject(s) - supramolecular chemistry , monomer , chemistry , mannose , amphiphile , supramolecular polymers , mannose receptor , antigen , peptide , copolymer , polymer , biochemistry , biology , molecule , immunology , organic chemistry , in vitro , macrophage
The cover feature picture shows the supramolecular copolymerisation of a dendritic peptide amphiphile monomer bearing mannosides and a second monomer carrying tetra(ethylene glycol)s and labelled with a Cy3 fluorescent probe. The multicomponent mannose‐decorated copolymers trigger the uptake into macrophages as antigen‐presenting cells that play a key role in the innate immune response. More information can be found in the communication by E. Schmitt, P. Besenius et al. on page 912 in Issue 9, 2018 (DOI: 10.1002/cbic.201800114)