Premium
Selective Imaging of Lipids in Adipocytes by Using an Imidazolyl Derivative of Perylene Bisimide
Author(s) -
Mishra Ruchika,
Mushtaq Zeeshan,
Regar Ramprasad,
Mallik Bhagaban,
Kumar Vimlesh,
Sankar Jeyaraman
Publication year - 2018
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201800134
Subject(s) - perylene , derivative (finance) , fluorescence , chemistry , photochemistry , molecule , biophysics , biology , organic chemistry , physics , quantum mechanics , financial economics , economics
A small molecule, perylene bisimide imidazolyl derivative (PBI‐ID), has been identified and developed as a specific marker for labelling multifunctional fat bodies in various organisms, including Drosophila and mammalian adipocytes. Interestingly, PBI‐ID neither labels the plasma membranes nor cell nuclei by trapping into it. A remarkable feature of unbound PBI‐ID is diminished fluorescence, which reduces the background emission noise, while contrasting the bound state effectively.