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Inside Back Cover: A Tandem Enzymatic sp 2 ‐C‐Methylation Process: Coupling in Situ S‐Adenosyl‐ l ‐Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)
Author(s) -
Sadler Joanna C.,
Humphreys Luke D.,
Snajdrova Radka,
Burley Glenn A.
Publication year - 2017
Publication title -
chembiochem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201700244
Subject(s) - tandem , in situ , methionine , methylation , chemistry , methyltransferase , enzyme , stereochemistry , coupling (piping) , biochemistry , amino acid , organic chemistry , dna , mechanical engineering , materials science , engineering , composite material
The inside back cover picture shows a one‐pot tandem reaction involving in situ enzymatic synthesis of S‐adenosylmethionine by using SalL, followed by C−C bond formation by using the C‐methyltransferase NovO. This system is compatible with both methionine and methionine analogues as the alkyl donor. More information can be found in the communication by L. D. Humphreys, G. A. Burley et al. on page 992 in Issue 11, 2017 (DOI: 10.1002/cbic.201700115).