Inside Cover: Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells (ChemBioChem 4/2017) | Zendy

Tachibana Ryo | Zendy; Terai Takuya | Zendy; Boncompain Gaelle | Zendy; Sugiyama Shigeru | Zendy; Saito Nae | Zendy; Perez Franck | Zendy; Urano Yasuteru | Zendy

Premium

Inside Cover: Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells (ChemBioChem 4/2017)

Author(s) -

Tachibana Ryo,

Terai Takuya,

Boncompain Gaelle,

Sugiyama Shigeru,

Saito Nae,

Perez Franck,

Urano Yasuteru

Publication year - 2017

Publication title -

chembiochem

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.201700035

Subject(s) - streptavidin , solubility , treasure , chemistry , front cover , combinatorial chemistry , nanotechnology , biotin , cover (algebra) , materials science , biochemistry , organic chemistry , engineering , philosophy , mechanical engineering , theology

The inside cover picture shows an improvement in the solubility of artificial ligands of streptavidin (ALiS). The previously reported compound, ALiS‐1 ( ninja at front), cannot access streptavidin (SAv, gold treasure) in cells because of poor water solubility in the absence of organic cosolvent such as DMSO ( samurai ). On the other hand, the new compound, ALiS‐3 (the other ninja ), has higher solubility in water and can reach SAv inside cells; this is represented by his tricky art of escape from the samurai by using water ( suiton‐no‐jutsu ). Picture by R.T. More information can be found in the communication by Takuya Terai, Yasuteru Urano et al. on page 358 in Issue 4, 2017 (DOI: 10.1002/cbic.201600640).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research