Inside Cover: Exploring the Potential of Norbornene‐Modified Mannosamine Derivatives for Metabolic Glycoengineering (ChemBioChem 14/2016) | Zendy

Späte AnneKatrin | Zendy; Dold Jeremias E. G. A. | Zendy; Batroff Ellen | Zendy; Schart Verena F. | Zendy; Wieland Daniel E. | Zendy; Baudendistel Oliver R. | Zendy; Wittmann Valentin | Zendy

Premium

Inside Cover: Exploring the Potential of Norbornene‐Modified Mannosamine Derivatives for Metabolic Glycoengineering (ChemBioChem 14/2016)

Author(s) -

Späte AnneKatrin,

Dold Jeremias E. G. A.,

Batroff Ellen,

Schart Verena F.,

Wieland Daniel E.,

Baudendistel Oliver R.,

Wittmann Valentin

Publication year - 2016

Publication title -

chembiochem

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.201600355

Subject(s) - bioorthogonal chemistry , tetrazine , chemistry , monosaccharide , glycan , cover (algebra) , combinatorial chemistry , biochemistry , click chemistry , organic chemistry , glycoprotein , engineering , mechanical engineering

The inside cover picture shows how metabolic glycoengineering can be explained in a creative way (idea: Sven Epple). Modified monosaccharides are used to engineer the cell surfaces’ glycans with functional groups. Surprisingly, bulky norbornenes can also be used as modifiers. In a second step, these modifications are “colored” through a bioorthogonal ligation reaction with a tetrazine or cyclooctyne that is linked to a label. More information can be found in the full paper by V. Wittmann et al. on page 1374 in Issue 14, 2016 (DOI: 10.1002/cbic.201600197).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research