Back Cover: Structural Integrity of the A147T Polymorph of Mammalian TSPO (ChemBioChem 10/2015) | Zendy

Jaremko Mariusz | Zendy; Jaremko Łukasz | Zendy; Giller Karin | Zendy; Becker Stefan | Zendy; Zweckstetter Markus | Zendy

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Back Cover: Structural Integrity of the A147T Polymorph of Mammalian TSPO (ChemBioChem 10/2015)

Author(s) -

Jaremko Mariusz,

Jaremko Łukasz,

Giller Karin,

Becker Stefan,

Zweckstetter Markus

Publication year - 2015

Publication title -

chembiochem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.201590027

Subject(s) - chemistry , tryptophan , side chain , stereochemistry , amino acid , biophysics , crystallography , biochemistry , biology , organic chemistry , polymer

The back cover picture shows that A147T polymorphism does not perturb the structure or dynamics of mammalian TSPO. On p. 1483 ff., M. Zweckstetter et al. show that crucial side chains in the cholesterol recognition amino acid consensus (CRAC) motif have the same orientation in the wild‐type (grey) and A147T variant (orange), but not in the tryptophan‐rich sensory protein from R. sphaeroides (pink).

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