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Back Cover: Directed Divergent Evolution of a Thermostable D ‐Tagatose Epimerase towards Improved Activity for Two Hexose Substrates (ChemBioChem 4/2015)
Author(s) -
Bosshart Andreas,
Hee Chee Seng,
Bechtold Matthias,
Schirmer Tilman,
Panke Sven
Publication year - 2015
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201590008
Subject(s) - cover (algebra) , chemistry , hexose , biochemistry , enzyme , mechanical engineering , engineering
The back cover picture shows how evolving biocatalysts is an essential part of the emerging bioeconomy. In their paper on p. 592 ff, S. Panke and co‐workers report how they divergently evolved a D ‐tagatose epimerase into much improved catalysts to produce D ‐psicose from fructose and L ‐tagatose from L ‐sorbose, identifying the underlying molecular reasons from detailed crystal structures.