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Back Cover: The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation (ChemBioChem 15/2015)
Author(s) -
Waldman Abraham J.,
Pechersky Yakov,
Wang Peng,
Wang Jennifer X.,
Balskus Emily P.
Publication year - 2015
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201500461
Subject(s) - gene cluster , diazo , streptomyces , gene , heterologous expression , biosynthesis , heterologous , metabolite , streptomyces albus , secondary metabolite , biology , chemistry , stereochemistry , genetics , biochemistry , bacteria , recombinant dna , organic chemistry
The back cover picture shows a mosaic graphic of Streptomyces cremeus growing on an agar plate. Expression of the cremeomycin biosynthetic gene cluster in Streptomyces lividans represents the only successful heterologous production of a diazo‐containing metabolite to date and provides the first experimental link between a set of genes and diazo formation.