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Back Cover: SUMO‐Mimicking Peptides Inhibiting Protein SUMOylation (ChemBioChem 18/2014)
Author(s) -
Zhao Bo,
Villhauer Eric B.,
Bhuripanyo Karan,
Kiyokawa Hiroaki,
Schindelin Hermann,
Yin Jun
Publication year - 2014
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201490066
Subject(s) - sumo protein , cover (algebra) , peptide , chemistry , posttranslational modification , sumo enzymes , enzyme , protein engineering , computational biology , biochemistry , biophysics , microbiology and biotechnology , combinatorial chemistry , nanotechnology , biology , engineering , materials science , ubiquitin , gene , mechanical engineering
The back cover picture shows that the SUMO protein has been downsized by protein engineering to a heptamer short peptide that can be activated and transferred through the E1 and E2 enzymes to RanGAP1, a SUMO modification target in the cell. For details, see the paper by J. Yin et al. on p. 2662 ff .