Premium
Back Cover: Hydrophobic Triaryl‐Substituted β‐Lactams as Activity‐Based Probes for Profiling Eukaryotic Enzymes and Host–Pathogen Interactions (ChemBioChem 15/2014)
Author(s) -
Nasheri Neda,
McKay Craig S.,
Fulton Kelly,
Twine Susan,
Powdrill Megan H.,
Sherratt Allison R.,
Pezacki John Paul
Publication year - 2014
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201490054
Subject(s) - enzyme , cover (algebra) , pathogen , profiling (computer programming) , chemistry , host (biology) , computational biology , biology , biochemistry , combinatorial chemistry , microbiology and biotechnology , genetics , mechanical engineering , computer science , engineering , operating system
The back cover picture shows a β‐lactam activity‐based probe that can report on a broad range of enzyme activities at one time. This non‐directed probe captures HCV‐induced changes in the activity of mechanistically distinct enzymes that could be potential biomarkers of viral infection. For more details, see the communication by J. P. Pezacki and co‐workers on p. 2195 ff.