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Inside Cover: Structural Basis of Furan–Amino Acid Recognition by a Polyspecific Aminoacyl‐tRNA‐Synthetase and its Genetic Encoding in Human Cells (ChemBioChem 12/2014)
Author(s) -
Schmidt Moritz J.,
Weber Annemarie,
Pott Moritz,
Welte Wolfram,
Summerer Daniel
Publication year - 2014
Publication title -
chembiochem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201490042
Subject(s) - aminoacyl trna synthetase , cover (algebra) , amino acid , transfer rna , genetic code , furan , chemistry , computational biology , basis (linear algebra) , biology , biochemistry , combinatorial chemistry , gene , organic chemistry , rna , mechanical engineering , geometry , mathematics , engineering
The inside cover picture shows a structural overview of a polyspecific pyrrolysyl–tRNA‐synthetase mutant used to genetically encode a furan‐bearing lysine amino acid. The large amino acid binding pocket of the mutant enzyme can accommodate bulky amino acid side chains. For more details, see the communication by D. Summerer and co‐workers on p. 1755 ff.