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A Bacterial Mutant Library as a Tool to Study the Attack of a Defensin Peptide
Author(s) -
Moser Simone,
Chileveru Haritha R.,
Tomaras Jill,
Nolan Elizabeth M.
Publication year - 2014
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201402354
Subject(s) - defensin , peptide , bacteria , mutant , biology , microbiology and biotechnology , chemistry , biochemistry , genetics , gene
Defensin attack! Here we report the screening of human defensin 5 against the Keio Collection of E. coli s trains. The results of this screen further our understanding of how this important hostdefense peptide kills bacteria and how bacteria protect themselves against the attack from the human host.