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Sortase‐Based Bio‐organic Strategies for Macromolecular Synthesis
Author(s) -
Haridas V.,
Sadanandan Sandhya,
Dheepthi N. U.
Publication year - 2014
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201402013
Subject(s) - sortase , ligation , macromolecule , chemistry , sortase a , organic molecules , molecule , small molecule , combinatorial chemistry , nanotechnology , computational biology , biochemistry , bacterial protein , biology , organic chemistry , materials science , microbiology and biotechnology , gene
Protein ligation sorted : SrtA is one of the molecules nature uses to perform chemoselective ligation on amazingly complex protein molecules. Sortase‐mediated ligation (SML) with chemoselective reactions will find a variety of applications in chemistry, biology, and medicine in the near future.