Inside Cover: Glycan Sequence‐Dependent Nod2 Activation Investigated by Using a Chemically Synthesized Bacterial Peptidoglycan Fragment Library (ChemBioChem 4/2013) | Zendy

Wang Ning | Zendy; Huang Chengyuan | Zendy; Hasegawa Mizuho | Zendy; Inohara Naohiro | Zendy; Fujimoto Yukari | Zendy; Fukase Koichi | Zendy

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Inside Cover: Glycan Sequence‐Dependent Nod2 Activation Investigated by Using a Chemically Synthesized Bacterial Peptidoglycan Fragment Library (ChemBioChem 4/2013)

Author(s) -

Wang Ning,

Huang Chengyuan,

Hasegawa Mizuho,

Inohara Naohiro,

Fujimoto Yukari,

Fukase Koichi

Publication year - 2013

Publication title -

chembiochem

Language(s) - English

Resource type - Reports

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.201390009

Subject(s) - glycan , peptidoglycan , chemistry , tetrasaccharide , sequence (biology) , nod2 , fragment (logic) , stereochemistry , biochemistry , enzyme , combinatorial chemistry , glycoprotein , polysaccharide , programming language , receptor , computer science , innate immune system

The inside cover picture shows glycan‐sequence‐dependent human Nod2 recognition of PGN fragments. On p. 482 ff. , Y. Fujimoto, K. Fukase, et al. report how they chemically synthesized a range of di‐ or tetrasaccharide fragments of PGN, and showed that (MurNAcβ(1→4)GlcNAc) 2 ‐containing structures exhibited stronger activity than those containing (GlcNAcβ(1→4)MurNAc) 2 , produced with different enzymatic degradation process.

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