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Enzymatic Aerobic Alkene Cleavage Catalyzed by a Mn 3+ ‐Dependent Proteinase A Homologue
Author(s) -
Rajagopalan Aashrita,
Schober Markus,
Emmerstorfer Anita,
Hammerer Lucas,
Migglautsch Anna,
Seisser Birgit,
Glueck Silvia. M.,
Niehaus Frank,
Eck Juergen,
Pichler Harald,
Gruber Karl,
Kroutil Wolfgang
Publication year - 2013
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201300601
Subject(s) - alkene , chemistry , cleavage (geology) , enzyme , stereochemistry , manganese , catalysis , biochemistry , organic chemistry , biology , paleontology , fracture (geology)
New clothes for Mn 3+ : Aerobic alkene cleavage of styrene‐type substrates by Trametes hirsuta is attributed to an enzyme that is dependent on manganese in oxidation state three. The enzyme has a proteinase backbone and binds Mn 3+ exclusively via oxygen atoms, in contrast to all known Mn 3+ enzymes.

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