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Construction of a Biomimetic Peroxynitrite‐Generating Platform: A Two‐Component System to Synthesize Peroxynitrite in Situ under the Control of Light
Author(s) -
de BoerMaggard Tara R.,
Resendez Angel,
Mascharak Pradip K.
Publication year - 2013
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201300488
Subject(s) - peroxynitrite , chemistry , xanthine oxidase , in situ , component (thermodynamics) , layer (electronics) , nanotechnology , biochemistry , materials science , organic chemistry , superoxide , enzyme , physics , thermodynamics
Surge protector: A two‐component peroxynitrite‐generating platform has been engineered to release peroxynitrite (PN) in situ under the control of light. The system, which is constructed by layering sol–gel matrices containing xanthine oxidase (bottom layer) and a metal nitrosyl (top layer), allows studies of PN chemistry at varying fluxes of its precursors.