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“Rolling out” High‐Molecular‐Weight Proteins, which Contain Repeating Polypeptide Motif, by Using Rolling Circle Amplification
Author(s) -
Zheng Yue,
Sintim Herman O.
Publication year - 2013
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201300415
Subject(s) - ribosome , polypeptide chain , rolling circle replication , motif (music) , messenger rna , biology , computational biology , chemistry , biochemistry , microbiology and biotechnology , genetics , gene , amino acid , rna , physics , polymerase , acoustics
Keep going round in circles: On a circular mRNA template and without an end in sight, E. coli ribosomes have no option but to keep on making a high‐molecular‐weight polypeptide with repeating units. In this Highlight, the recently published work by Abe and co‐workers on this topic is discussed.