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Inside Cover: The α‐Ketoglutarate/Fe II ‐Dependent Dioxygenase VldW Is Responsible for the Formation of Validamycin B (ChemBioChem 15/2012)
Author(s) -
Almabruk Khaled H.,
Asamizu Shumpei,
Chang Ada,
Varghese Sheril G.,
Mahmud Taifo
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201290063
Subject(s) - streptomyces hygroscopicus , chemistry , dioxygenase , stereochemistry , cover (algebra) , streptomyces , biochemistry , biology , enzyme , bacteria , genetics , mechanical engineering , engineering
The inside cover picture shows the conversion of validamycin A to validamycin B catalyzed by the α‐ketoglutarate/Fe II ‐dependent dioxygenase VldW in Streptomyces hygroscopicus subsp. limoneus. Validamycin A is an important crop‐protectant and the precursor of the antidiabetic drug voglibose. For further details see the paper by T. Mahmud et al. on p. 2209 ff.