Premium
Inside Cover: Generation of RNA Molecules by a Base‐Catalysed Click‐Like Reaction (ChemBioChem 7/2012)
Author(s) -
Costanzo Giovanna,
Saladino Raffaele,
Botta Giorgia,
Giorgi Alessandra,
Scipioni Anita,
Pino Samanta,
Di Mauro Ernesto
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201290025
Subject(s) - formamide , polymerization , click chemistry , cover (algebra) , chemistry , monomer , base (topology) , polymer chemistry , dimethylformamide , ene reaction , molecule , organic chemistry , polymer , solvent , mechanical engineering , mathematical analysis , mathematics , engineering
The inside cover picture shows the spontaneous polymerization of 3′,5′‐cyclic GMP occurring in water, in formamide, in dimethylformamide, and (in water) in the presence of a Brønsted base such as 1,8‐diazabicycloundec‐7‐ene. The polymerization occurs among stacked monomers, is thermodynamically favoured and selectively yields 3′,5′‐bonded ribopolymers. For further details see the paper by E. Di Mauro et al. on p. 999 ff.