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Genetic Dissection of Sesquiterpene Biosynthesis by Fusarium fujikuroi
Author(s) -
Brock Nelson L.,
Huss Kathleen,
Tudzynski Bettina,
Dickschat Jeroen S.
Publication year - 2013
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200695
Subject(s) - sesquiterpene , metabolic engineering , biology , gibberella fujikuroi , terpene , gene , computational biology , fusarium , microbiology and biotechnology , computer science , genetics , botany , biochemistry
A treasure trove of terpenes: The products of two fungal sesquiterpene synthases from the rice pathogen Fusarium fujikuroi were identified by gene‐knockout experiments, genetic engineering of the fungus for production optimization, isolation of the sesquiterpenes, and structure elucidation by spectroscopic methods.