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Marine Cyanobacterial Fatty Acid Amides Acting on Cannabinoid Receptors
Author(s) -
Montaser Rana,
Paul Valerie J.,
Luesch Hendrik
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200502
Subject(s) - endocannabinoid system , cannabinoid receptor , receptor , cannabinoid , fatty acid , biochemistry , cyanobacteria , chemistry , computational biology , biology , bacteria , genetics , agonist
Striking cAMP: Certain fatty acid amides from marine cyanobacteria can mimic the endocannabinoids. Serinolamide B, a new analogue identified from a Guamanian sample, and malyngamide B, a representative member of a large class of cyanobacterial metabolites, can decrease forskolin‐induced cAMP accumulation through the cannabinoid receptors.

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