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A Template‐Assembled Synthetic U‐Quadruplex
Author(s) -
Hui Benjamin WeiQiang,
Sherman John C.
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200442
Subject(s) - cavitand , uracil , uridine , g quadruplex , chemistry , combinatorial chemistry , nucleobase , computer science , stereochemistry , computational biology , biochemistry , supramolecular chemistry , biology , rna , organic chemistry , molecule , dna , gene
Fo(u)r U: A lipophilic cavitand with four dinucleoside (uridine) residues has been synthesized and characterized. NMR spectroscopy evidence suggests the self‐assembly of a U‐quadruplex by the uracil nucleobases in organic solution under ambient conditions.
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