Complex Gadolinium–Oxo Clusters Formed along Concave Protein Surfaces | Zendy

Veelders Maik | Zendy; Essen LarsOliver | Zendy

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Complex Gadolinium–Oxo Clusters Formed along Concave Protein Surfaces

Author(s) -

Veelders Maik,

Essen LarsOliver

Publication year - 2012

Publication title -

chembiochem

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.05

H-Index - 126

eISSN - 1439-7633

pISSN - 1439-4227

DOI - 10.1002/cbic.201200441

Subject(s) - gadolinium , contrast (vision) , lanthanide , cluster (spacecraft) , biomolecule , chemistry , computational biology , nanotechnology , computer science , biochemistry , biology , materials science , artificial intelligence , organic chemistry , ion , programming language

Protein‐bound contrast: The unusual observation of a heptanuclear gadolinium–oxo cluster on the surface of the cell‐adhesion protein Flo5A establishes the basis for directed incorporation of poly‐lanthanide clusters into biomolecules. The observed gadolinium cluster might serve as a paradigm for the design of protein‐based MRI contrast agents.

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