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The Mechanosensitive Channel of Small Conductance (MscS) Superfamily: Not Just Mechanosensitive Channels Anymore
Author(s) -
Malcolm Hannah R.,
Maurer Joshua A.
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200410
Subject(s) - mechanosensitive channels , superfamily , ion channel , conductance , microbiology and biotechnology , biophysics , biology , chemistry , genetics , physics , receptor , condensed matter physics
A family of many talents: The mechanosensitive channel of small conductance (MscS) superfamily of ion channels is composed of 15 unique subfamilies. Many of these subfamilies are predicted to be nonmechanosensitive and to have evolved to play critical roles in bacterial signal transduction.