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Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles
Author(s) -
Reddy E. Ramanjaneya,
Banote Rakesh Kumar,
Chatti Kiranam,
Kulkarni Pushkar,
Rajadurai Marina S.
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200350
Subject(s) - zebrafish , fluorescence , fish <actinopterygii> , pyrene , nanoparticle , in vivo , benzo(a)pyrene , nanotechnology , biocompatible material , guanine , chemistry , biochemistry , biology , materials science , biomedical engineering , gene , fishery , medicine , physics , microbiology and biotechnology , optics , organic chemistry , nucleotide
Glowing fish: Fluorescent organic nanoparticles (FONs) were prepared from pyrene‐containing guanine analogues. FONs are able to penetrate into human cells and zebrafish embryos; they are nontoxic, biocompatible and were found to be specific for muscular tissues. This study demonstrates for the first time the possibility of using FONs for in vivo, whole‐body, fluorescence imaging of zebrafish.