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Chemical Biology Techniques Unlock the Secrets of Casein Kinase 2 Regulation by Phosphorylation and Glycosylation
Author(s) -
Pavic Karolina,
Köhn Maja
Publication year - 2012
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201200235
Subject(s) - glycosylation , phosphorylation , casein kinase 1 , kinase , casein kinase 2 , biology , dna microarray , protein phosphorylation , protein kinase a , biochemistry , computational biology , proteomics , microbiology and biotechnology , chemistry , cyclin dependent kinase 2 , gene , gene expression
The key to understanding: The application of expressed protein ligation and protein microarrays enabled an unparalleled insight into the complex interaction of phosphorylation and glycosylation on casein kinase 2 and its biological outcome.